I'm at the BELL Conference at Cornell University, and just came out of the Sustainable Innovation for Incumbents discussion, which addressed the challenges MNCs face when creating sustainable global enterprises, including those that tackle the BOP market.  The two main obstacles identified were:  1) how to change the corporate mindset, and 2) what skills / competencies are required.  Both were discussed in depth by the audience, who gave a variety of perspectives on the issues.